Kevin Bacon:Sebastian Caine / Hollow Man;Elisabeth Shue:Linda McKay;Josh Brolin:Matthew Kensington;Kim Dickens:Sarah Kennedy;Rhona Mitra:Sebastian's Neighbor;Greg Grunberg:Carter Abbey;Joey Slotnick:Frank Chase;Mary Randle:Janice Walton;William Devane:Dr. Howard Kramer;Pablo Espinosa:Ed, Warehouse Guard;Jeffrey Scaperrotta:Boy in Car (as Jeffrey George Scaperotta)