Robin Williams:Hunter 'Patch' Adams;Philip Seymour Hoffman:Mitch Roman;Bob Gunton:Dean Walcott;Peter Coyote:Bill Davis;Michael Jeter:Rudy;Monica Potter:Carin;Harve Presnell:Dean Anderson;Daniel London:Truman;Josef Sommer:Dr. Eaton;Irma P. Hall:Joletta;Frances Lee McCain:Judy;Daniella Kuhn:Adelane;James Greene:Bile;Harold Gould:Arthur Mendelson;Bruce Bohne:Trevor Beene;Harry Groener:Dr. Prack;Barry Shabaka Henley:Emmet;Steven Anthony Jones:Charlie;Richard Kiley:Dr. Titan;Douglas Roberts:Larry;Ellen Albertini Dow:Aggie;Alan Tudyk:Everton;Ryan Hurst:Neil;Peter Siteri:Chess Man;Don West:Instructor;Greg Sestero:Jaime (Monica Potter's brother);Jason Aaron Baca:Patch Pirate;Ismael 'East' Carlo:Hispanic Father;Diane Amos:Older Waitress;Andy Arness:Orderly (uncredited)